Older adults who received at least one flu vaccine were 40% less likely to develop Alzheimer’s disease

Sunday, June 26, 2022 • 7:40 EDT

Summary: Older adults who received at least one flu vaccination were 40% less likely to develop Alzheimer’s disease over the course of a four-year follow-up than their peers who did not receive a vaccine. “Future research should assess whether flu vaccination is also associated with the rate of symptom progression in patients who already have Alzheimer’s dementia.” The study—which comes two years after UTHealth Houston researchers found a possible link between the flu vaccine and reduced risk of Alzheimer’s disease—analyzed a much larger sample than previous research, including 935,887 flu-vaccinated patients and 935,887 non-vaccinated patients. Journal of Alzheimer’s Disease Risk of Alzheimer’s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching Prior studies have found a reduced risk of dementia of any etiology following influenza vaccination in selected populations, including veterans and patients with serious chronic health conditions. “We found that flu vaccination in older adults reduces the risk of developing Alzheimer’s disease for several years. People who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to develop Alzheimer’s disease over the course of four years, according to a new study from UTHealth Houston. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School, compared the risk of Alzheimer’s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of U.S. adults aged 65 and older. This study demonstrates that influenza vaccination is associated with reduced AD risk in a nationwide sample of US adults aged 65 and older. “Risk of Alzheimer’s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching” by Avram S. Bukhbinder et al. (neurosciencenews.com). Continue reading.



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