Microdosing psychedelics and creativity: a need for more research

When restricted to studies that follow double-blind and placebo-controlled experimental designs, considerably less evidence supports the positive effects of microdosing. The most frequently used compounds are LSD and psilocybin, the latter in the form of dried psychoactive mushrooms [7,8,9, 26]. In the case of psilocybin mushrooms, microdoses are within the range of 0.1 g to 0.5 g of dried mushroom material [18], with 0.1 g considered roughly equivalent to ≈4.6 µg of LSD [26]. As acknowledged by the authors of this study, 0.7 g exceeds what is frequently considered the upper limit when microdosing with psilocybin mushrooms (note, however, that what constitutes “microdosing” is not precisely defined) [25]. **p < 0.05, Bonferroni corrected (n = 4). There is considerable variability in dose and dosing schedules [25]. c Attentional blink. b Binocular rivalry. (). Continue reading.

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